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CYCLO-DIOL™ is sublingual tablet of Androdiol, 4-ANDROSTENE-3, 17 DIOL. It is an immediate precursor of testosterone that is converted in the body directly to testosterone. It has been shown to typically increase testosterone levels by approximately 125% in about 40 minutes and then drop off gradually over the next 2-3 hours.

When a prohormone is taken orally, it is subject to metabolism in the liver which inactivates most of it and delays its activity for up to several hours. The sublingual form is taken by placing it in the lining of the cheek or under the tongue and goes directly into the blood stream. It has an 85% absorption rate.

Another advantage of the sublingual form is that it does not need to be taken on an empty stomach, as the oral form does.

Studies have shown that 25 mg of sublingual CYCLO-DIOL™ will release more Testosterone than 100 mg of the oral ANDRODIOL®. The elevation is 134% more at 25 mg than 100 mg of the oral version. It only comes in 25 mg because anything higher will not be utilized.

Androdiol should not be confused with androstenedione, which can convert directly to estrogen. Androdiol converts directly to testosterone and cannot convert directly to estrogen.

Cyclodiol is the preferred prohormone for boosting testosterone levels because it works rapidly , does not need to be taken on an empty stomach and cannot convert directly to Estrogen like androstenedione does. Osmo has a patent on androdiol and guarantees that its product is pharmaceutical grade.

Dosage Recommendation:
Place one tablet under tongue and let dissolve completely. Can be taken once or twice per day: (i.e. once prior to exercise, and once in the evening.)

If sleep problems occur take the evening dose in the afternoon instead. Continue this routine even on your rest days. This product should be cycled. Take for 6-8 weeks, go off for about 2 weeks, and start cycle again.

Who should NOT take it?
Not for use by children, teenagers, pregnant or nursing women. Do not use this product if you have breast, uterine, ovarian or prostate problems. If you are under medical supervision, consult with your physician before taking product. Women should not take this product due to its masculine effects.

Consult your health care practitioner before taking this product.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.


Serving Size: 1 Tablet
Servings Per Container: 60

Cherry flavor

Amount Per Serving:

4-Androstene-3,17 diol: 25 mg
Hydroxypropyl- Beta-Cyclodextrin: 225 mg

Potency guaranteed by HPLC analysis

Other ingredients: Sorbitol, Natural Cherry Flavor, Stearic Acid, Magnesium Stearate.

SOURCE: Proceedings of the National Academy of Sciences (1997;94:7537-7542) Androstenediol (4-AD) is a natural occurring androgen metabolite, found in all animals (meat), and is both a direct precursor and metabolite to testosterone. It is a very obscure compound that is not widely discussed in the literature like other androgens are. In all mammals, 4AD is produced in the gonads and adrenal glands. The oral form of 4AD is metabolized in the liver to become testosterone via an enzymatic pathway.

This exciting new product is Androdiol in a sublingual cyclodextrin form. A University study revealed that Cyclo-Diol delivers 260% more testosterone conversion than 100mg of oral Androdiol.

When a prohormone is taken orally, it is subject to First Pass (the body breaks it down which is not good because it leaves very little active hormone life). The hormone is in and out of the system very quickly. Cyclodextrin is a molecule with a water compatible exterior and a water incompatible interior. The ANDRODIOL™ or NORANDRODIOL™ molecule is placed inside the Cyclodextrin.

The water compatible exterior of the Cyclodextrin will camouflage the water incompatible molecule, the pro-hormone. Your bloodstream will allow it to enter immediately, and the pro-hormone will be released into your body. It is taken by placing in the lining of the cheek or under the tongue. It goes directly into the blood stream. It works rapidly regardless of whether you have eaten recently or not.

In summary, cyclodextrin complexes taken sublingually (under the tongue) get pro-hormones into the bloodstream much better than orally taken capsules since over 90% of orally taken pro-hormones are never utilized by the body.