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CAL APATITE PLUS™

Cal Apatite Plus features calcium-rich microcrystalline hydroxyapatite concentrate (MCHC), a complex crystalline compound composed primarily of calcium, phosphorus, organic factors, and a full spectrum of trace minerals that naturally comprise healthy diet, can play a significant role in reducing the rate of bone loss or bone thinning and in protecting bone strength.

Calcium 440 mg
Ipriflavone (as Ostivone™) 100 mg
Microcrystalline Hydroxyapatite 1000 mg
Phosphorus 281 mg
Vitamin D (Cholecalciferol) 150 IU

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

CALCIUM is the most predominant mineral in bone tissue. The actual form of Calcium in bone is called "Hydroxyapatite." The most efficient way to feed our bones is to give them a "food" that they recognize, i.e. a type of calcium most similar in structure.

Hydroxyapatite Calcium, or purified bone meal harvested from range-grazed Australian beef cattle, is just such a Calcium. Whereas other types of Calcium can help prevent further loss of bone to one degree or another, Hydroxyapatite is one of the two types of calcium known to actually regenerate bone tissue.

An important study of calcium supplementation was undertaken by the Dept. of Medicine and Radiology at the Royal Free Hospital in London, England in 1981 and reported in 1982. 3 Fifty-three post-menopausal women diagnosed to have seriously impaired calcium absorption and accelerated bone loss were separated into three groups and studied for over 14 months. At the start of the study, all participants had their forearm bones measured by X-ray radiogrammetry. The groups were comprised as follows:

1) Control (Vitamin D only): 21

2) Calcium Gluconate and Vitamin D: 17

3) Hydroxyapatite and Vitamin D: 15

All groups received intramuscular injections of 100,000 units of Vitamin D each month. (This was a carefully controlled medical study. Do not take this high amount on your own.)

The Second group received 1000 mg. per day of organic Calcium (as gluconate).

The Third group received 1000 mg. per day of elemental Calcium derived from Hydroxyapatite.

At the end of the 14 month period, follow-up measurements of the forearm bones showed the Control group (Vitamin D only) had a "significant loss of cortical bone."

The Calcium Gluconate and Vitamin D group showed virtually "no change" in bone status from the beginning of the study. But the Hydroxyapatite and Vitamin D group showed "a significant increase in bone thickness."

An 18-Year Prospective Study of Dietary Calcium and Bone Mineral Density in the Hip


Author(s): Holbrook TL, Barrett-Connor E
Source: Calcified Tissue Int. 1995; 56:364-367.

Abstract:

The object of this study was to determine whether a single 24-hour diet recall of calcium intake obtained an average of 18 years previously would predict bone mineral density (BMD) in the hip in older men and women. A prospective population-based cohort study was done in Rancho Bernardo, California. Between 1973 and 1975, a 24-hour diet recall was obtained in 140 men and 220 women aged 45 and older by a trained interviewer using food models and containers. Responses were coded by the Nutrition Coordinating Center, University of Minnesota. Between 1988 and 1991, BMD in the femoral neck, trochanter,
and intertrochanter was measured using dual-energy x-ray absorptiometry. Results showed that age-adjusted mean BMD levels
increased significantly with increasing tertile of calcium intake at all hip sites in women, with the most striking difference at the femoral neck. These associations persisted after adjustment for body mass index, smoking, exercise, alcohol intake, use of estrogen replacement therapy, and number of years postmenopausal. No significant trends were seen for men at any hip site. It is concluded that low dietary calcium predicts low BMD in older women independent of other major determinants of BMD.

Effect of Calcium and Vitamin D Supplementation on Bone Density in Men and Women 65 Years of Age or Older

Author(s): Dawson-Hughes B, Harris SS, Krall EA, Dallal GE
Source: N Engl J Med. 1997; 337:670-676.

Abstract:

Background Inadequate dietary intake of calcium and vitamin D may contribute to the high prevalence of osteoporosis among older persons.

Methods

We studied the effects of three years of dietary supplementation with
calcium and vitamin D on bone mineral density, biochemical measures of bone metabolism, and the incidence of nonvertebral fractures in 176 men and 213 women 65 years of age or older who were living at home. They received either 500 mg of calcium plus 700 IU of vitamin D3 (cholecalciferol) per day or placebo. Bone mineral density was measured by dual-energy x-ray absorptiometry, blood and urine were analyzed every six months, and cases of nonvertebral fracture were ascertained by means of interviews and verified with use of hospital records.

Results The mean (ฑSD) changes in bone mineral density in the calcium-vitamin D and placebo groups were as follows: femoral neck, +0.50ฑ4.80 and -0.70ฑ5.03 percent, respectively (P=0.02); spine +2.12ฑ4.06 and +1.22ฑ4.25 percent (P=0.04), and total body, +0.06ฑ1.83 and -1.09ฑ1.71 percent (P<0.001).

The difference between the calcium-vitamin D and placebo groups was significant at all skeletal sites after one year, but it was significant only for total-body bone mineral density in the second and third years. Of 37 subjects who had nonvertebral fractures, 26 were in the placebo group and 11 were in the calcium-vitamin D group (P=0.02).

Conclusions In men and women 65 years of age or older who are living in the community, dietary supplementation with calcium and vitamin D moderately reduced bone loss measured in the femoral neck, spine, and total body over the three-year study period and reduced the incidence of nonvertebral fractures.

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270 tablets    $57.95